The pancake syndrome (oral mite anaphylaxis) by ingestion and inhalation in a 52-year-old woman in the northeastern United States.

B-cell dysfunction. In summary, CVID is a heterogeneous immunodeficiency syndrome that spans a broad clinical spectrum. A small subset of patients with a presumptive diagnosis of CVID is spared recurrent infections despite hypogammaglobulinemia and impaired antibody responses to vaccines. Identification and registry of these patients will lead to broader awareness of CVID and will offer an opportunity to study potential innate mechanisms harnessed by the immune system to compensate for cognate defects.